Psycho-Babble Medication Thread 65482

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All that jitters... (social)

Posted by jimmygold70 on June 5, 2001, at 16:09:24

I think jitters is the word. That's what I feal when people are around me: I am not anxious, I feel some jitters, very uneasy, but I have no problem to speak up, say anything in front of people (even new). I am not shy. This is no kind of social phobia. I just feel restless near people.

I was diagnosed as having Borderline - Schizoid Personality Disorders. The jitters probably come from the schizoid side of my personality.

Anti-social-phobia drugs never helped (MAOIs, SSRIs, Effexor). Xanax was better, Klonopin even better. I had more side effects then usual, though.

My best experience so far was on Dekapote (divalproex). I feel much better near people. This isn't perfect yet, but still better. My PDoc added reboxetine lately against my depression, so I feel much worse right now and the jitters are back.

Anyone with similar experince with Mood Stabilizers counteracting 'social jitters' (but not pure phobia!) ? I wonder if anything will do better than Dekapote.

Jimmy

 

Re: All that jitters... (social) » jimmygold70

Posted by SalArmy4me on June 5, 2001, at 23:26:47

In reply to All that jitters... (social), posted by jimmygold70 on June 5, 2001, at 16:09:24

Gabapentin.

Pande, Atul C. MD, FRCPC et al. Treatment of Social Phobia With Gabapentin: A Placebo-Controlled Study. J of Clin Psypharm. 19(4):341-348, Aug 99.
{NOT FROM MEDLINE}
"This study has shown that gabapentin produced a significantly greater decrease in the symptoms of social phobia than did placebo as measured by the LSAS. Treatment response seemed to be influenced by age and gender, an observation for which only speculative explanations can be offered. Because women exhibited greater responses to placebo, the drug-placebo treatment difference was smaller for women than for men. Despite the influence of these variables, gabapentin seems to have anxiolytic activity, which confirms the anxiolytic profile seen in preclinical behavioral experiments."

 

Re: All that jitters... (social) jimmygold70

Posted by AMenz on June 8, 2001, at 0:33:33

In reply to Re: All that jitters... (social) » jimmygold70, posted by SalArmy4me on June 5, 2001, at 23:26:47

Jimmi,

Probably you have the jitters because of the anti-depressant. This schizoid diagnosis is something to take with a grain of salt.

It sounds like you may have a mood disorder. They're had to diagnose and specially bipolar II and you may wind up with interim diagnosis.

Are the jitters continuous since the AD was added or cyclical. Since SSRI's were added to my cocktail I also had mixed symptoms (anxiety depression and hypomania all together). These disappeared when I reduced the dose. However the SSRI was better for social anxiety.

Insofar as social anxiety is concerned. It comes I guess in many forms. I am also not shy and was more than willing to speak up etc as a child. However with the onset of bipolar disorder these symptoms started appearing. I think it is anxiety trigerred by fear that if I get too close to people they will reject me because of my symptoms. This is not a crazy idea since it does happen.

I would not discount that jitters are social anxiety even if what you feel is uncomforteable as opposed to scared.

I had a bad reaction to gabepentin although others in this site have not. I would recommend that you do not go off your basic stabilizer. The doctor can prescribe a second one as an adjunct to treatment.

For ex, going of lithium altogether, and substituting lamotrigine, then neurontin then topomax (one at a time) proved disastrous for me.

> Gabapentin.
>
> Pande, Atul C. MD, FRCPC et al. Treatment of Social Phobia With Gabapentin: A Placebo-Controlled Study. J of Clin Psypharm. 19(4):341-348, Aug 99.
> {NOT FROM MEDLINE}
> "This study has shown that gabapentin produced a significantly greater decrease in the symptoms of social phobia than did placebo as measured by the LSAS. Treatment response seemed to be influenced by age and gender, an observation for which only speculative explanations can be offered. Because women exhibited greater responses to placebo, the drug-placebo treatment difference was smaller for women than for men. Despite the influence of these variables, gabapentin seems to have anxiolytic activity, which confirms the anxiolytic profile seen in preclinical behavioral experiments."


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