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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by petters on March 22, 2002, at 0:58:45
Hi Scott.
Aripiprazole is not available in my country, yet. Probably it will be at the end of this year.
Memantine is either not availabele here. I think it is only in Germany you can find this drug.
By the way. Have you tried vagus nervus - stimulation?
what about trypthofan? An old stratergi here is clomipramine + litium + tryptofan + (new option- lamotrigin)Take care.
Petters.
Posted by andys on October 9, 2002, at 12:13:48
In reply to Aripiprazole SLS, posted by petters on March 22, 2002, at 0:58:45
Several news articles have estimated end of December for final approval by the FDA.
Evidently, the FDA has made aripiprazole "approvable", and the story is that it's a matter of the FDA and Bristol-Meyers deciding on the final language for the drug insert, before it is approved. The story I have heard is that the drug is so clean (side effects), that Bristol wanted very minimal side effects statements. However, the FDA wants to add a warning about akathisia (urge to move), which showed up, even at mid-doses, in some patients. So final approval is stalled out, pending their negotiations on language. (for specifics on akathisia warning: http://www.namiscc.org/newsletters/February02/aripiprazole.htm ).
This is the end of the thread.
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