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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Eddie Sylvano on June 20, 2003, at 10:44:54
I've been reading up on different avenues of depression research (drugs outside the monoamine affective families), and have been interested in memantine, a drug used to treat dementia via glutamate antagonism. Since memory problems have been a major problem for me, it seemed of interest.
Anyway, the government is evidently planning a trial of memantine's efficacy as an antidepressant. If you live in the Maryland area, it might be worth a try...
http://clinicaltrials.gov/ct/show/NCT00040261
Posted by yesac on June 20, 2003, at 14:05:21
In reply to Tried everything else?, posted by Eddie Sylvano on June 20, 2003, at 10:44:54
Isn't Lamictal a glutamate antagonist?
Yeah, I was also very interested about getting away from the monoamine drugs since none of them seemed to be doing anything for me (with the exception of Parnate, which I just started so it's too early to tell).
Posted by Eddie Sylvano on June 20, 2003, at 14:39:10
In reply to Re: Tried everything else? » Eddie Sylvano, posted by yesac on June 20, 2003, at 14:05:21
> Isn't Lamictal a glutamate antagonist?
Partly, which is mentioned in the study summary as evidence for a glutamate theory of depression (since Lamictal has AD properties).
Posted by HenryO on June 21, 2003, at 4:22:17
In reply to Tried everything else?, posted by Eddie Sylvano on June 20, 2003, at 10:44:54
Have you tried Lamictal?
Posted by Eddie Sylvano on June 22, 2003, at 15:20:41
In reply to Have you tried Lamictal?, posted by HenryO on June 21, 2003, at 4:22:17
> Have you tried Lamictal?
No, but I'm certainly curious. My PCP will only deal in low dose SSRIs (which actually seem to make some things worse), though I finally have an appointment with a real pdoc, so maybe some day.
This is the end of the thread.
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