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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by liquidchakra on February 27, 2004, at 8:05:46
It seems that alot of the problems down there are caused by its tendency to swell the prostate up; the prostate has loads of NE receptors apparently. Has anyone ever tried to take Saw Palmetto to fix this? I read before that it is nearly as effective as the leading prescription (Flomax), and one of the side effects of Flomax is priapism. I don't want that, but anything that has something to do with an erection as a side effect would be a great benifit to anyone on Strattera.
Posted by francesco on February 27, 2004, at 21:08:53
In reply to To all men with sexual side effects on Strattera, posted by liquidchakra on February 27, 2004, at 8:05:46
> It seems that alot of the problems down there are caused by its tendency to swell the prostate up; the prostate has loads of NE receptors apparently. Has anyone ever tried to take Saw Palmetto to fix this? I read before that it is nearly as effective as the leading prescription (Flomax), and one of the side effects of Flomax is priapism. I don't want that, but anything that has something to do with an erection as a side effect would be a great benifit to anyone on Strattera.
I don't know nothing about using Saw Palmetto to counteract Strattera's side-effects but I took Saw Palmetto alone for my prostatis and it gave me impotence. I have read that is a well known side effect of it. Where have you read about the connection between NE-reuptake and prostate problems ? I'm asking because I developed a prostatis after a short trial of Wellbutrin six months ago and since then I have always wondered if there was a connection. Thanks in advance
Posted by liquidchakra on March 1, 2004, at 10:33:03
In reply to Re: To all men with sexual side effects on Strattera » liquidchakra, posted by francesco on February 27, 2004, at 21:08:53
> > It seems that alot of the problems down there are caused by its tendency to swell the prostate up; the prostate has loads of NE receptors apparently. Has anyone ever tried to take Saw Palmetto to fix this? I read before that it is nearly as effective as the leading prescription (Flomax), and one of the side effects of Flomax is priapism. I don't want that, but anything that has something to do with an erection as a side effect would be a great benifit to anyone on Strattera.
>
> I don't know nothing about using Saw Palmetto to counteract Strattera's side-effects but I took Saw Palmetto alone for my prostatis and it gave me impotence. I have read that is a well known side effect of it. Where have you read about the connection between NE-reuptake and prostate problems ? I'm asking because I developed a prostatis after a short trial of Wellbutrin six months ago and since then I have always wondered if there was a connection. Thanks in advance
>
Sorry for the delay, I was out for the weekend.Quote (From http://www.mc.uky.edu/pharmacology/instruction/pha824ar/PHA824ar.html):
Tamsulosin has a similar action and is also used to treat BPH. Tamsulosin is an example of a drug that is selective for one of the subtypes of the alpha1-adrenergic receptors. This ligand selectively blocks the alpha1A-receptor. The alpha1A-receptor is involved in regulating the smooth muscle tone associated with the prostate. Therefore, tamsulosin selectively antagonizes the receptor subtype involved in regulating prostate function. Tamsulosin is less likely than the prazosin analogs to cause hypotension.
Alpha a-1 receptors are stimulated by norepinepherine. NARI's increase the level of NE, so there is more around to activate the receptor. There is a class of drugs for BPH that agonize the alpha a-1 receptor, and they reduce prostate swelling.
Thats odd that you say it gave you impotence. I heard the exact opposite (Better sex drive and a cure for impotence). How long were you taking it for and at what dose?
Posted by francesco on March 1, 2004, at 14:44:11
In reply to Re: To all men with sexual side effects on Strattera, posted by liquidchakra on March 1, 2004, at 10:33:03
> Thats odd that you say it gave you impotence. I heard the exact opposite (Better sex drive and a cure for impotence). How long were you taking it for and at what dose?I can't remember the dose, I took it for 2 months. I have read many things on the net about Saw Palmetto and impotence and this connection has been confirmed to me by two urologists. Anyway maybe my situation is different since I have prostatitis ...
check this out for example (I didn't read it, just type on Google 'impotence' and 'saw palmetto')
http://www.stevenfoster.com/education/monograph/sawpalmetto.htmlit says: "The saw palmetto product produced fewer complaints of decreased libido or impotence"
my understanding of this is that it CAN cause decreased libido and impotence
anyway, if you have read opposite things on saw palmetto, please post them ! I should have to take it again but I'm doubtful becuase of the impotence thing. Thanks !
Posted by King Vultan on March 2, 2004, at 17:12:35
In reply to To all men with sexual side effects on Strattera, posted by liquidchakra on February 27, 2004, at 8:05:46
> It seems that alot of the problems down there are caused by its tendency to swell the prostate up; the prostate has loads of NE receptors apparently. Has anyone ever tried to take Saw Palmetto to fix this? I read before that it is nearly as effective as the leading prescription (Flomax), and one of the side effects of Flomax is priapism. I don't want that, but anything that has something to do with an erection as a side effect would be a great benifit to anyone on Strattera.
>Drugs that block NE reuptake often do this, and if they are also strongly anticholinergic (Strattera is not; most of the tricyclics are), it will exacerbate the problem. Any of the alpha-1 blockers will deal with the problem, but Flomax has the least effect on blood pressure. It is also the most expensive. I've used it with good results but am switching to something cheaper because I cannot afford the $50/month copay under my idiotic health plan.
IMO, it is silly to worry about the priapism associated with Flomax because it is only about a 1/50,000 chance. If you are taking an alpha agonist such as Strattera, anyway, your chances of getting priapism are further reduced (treatment for priapism consists of injecting alpha agonists into the penis). Any of the alpha blockers has the potential to cause priapism, and I believe this is also the major reason trazodone is associated with priapism, as this drug has a relatively strong alpha-1 blockade (and a fairly strong alpha-2 blockade, which will further increase arousal as yohimbine does).
Todd
Posted by francesco on March 2, 2004, at 17:26:51
In reply to Re: To all men with sexual side effects on Strattera, posted by King Vultan on March 2, 2004, at 17:12:35
I have prostatitis and I have just begun a therapy with 10mg of Anafranil. Do you think that it can make it worse ? Thanks
Posted by King Vultan on March 3, 2004, at 12:37:39
In reply to Re: To all men with sexual side effects on Strattera » King Vultan, posted by francesco on March 2, 2004, at 17:26:51
> I have prostatitis and I have just begun a therapy with 10mg of Anafranil. Do you think that it can make it worse ? Thanks
10 mg is not very much unless you are a poor 2D6 metabolizer. I would expect to see difficulties more at higher levels. Anafranil's major effect is on serotonin, and it is not as proportionally strong on NE reuptake as are most of the other tricyclics. It is anticholinergic, but again, 10 mg would generally be considered not much of a dosage.
Todd
Posted by francesco on March 3, 2004, at 13:01:59
In reply to Re: To all men with sexual side effects on Strattera, posted by King Vultan on March 3, 2004, at 12:37:39
This is the end of the thread.
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