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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by ed_uk on January 3, 2005, at 20:28:53
To everyone with bipolar disorder...........
In your own personal experience.........
Which ADs *have not* induced mania, hypomania, mixed affective states or rapid cycling?
Which ADs *have* induced mania, hypomania, mixed episodes or rapid cycling?
PS. What do you think of the common pdoc attitude that TCAs are particularly likely to present problems in this respect? ....and that SSRIs and Wellbutrin are preferable. This doesn't seem particularly consistent with babblers' experiences. YMMV.
Posted by Phillipa on January 3, 2005, at 21:32:54
In reply to Antidepressants and Bipolar Disorder, posted by ed_uk on January 3, 2005, at 20:28:53
Glad to see you back on the Board! Phillipa O
Posted by Ritch on January 4, 2005, at 11:25:12
In reply to Antidepressants and Bipolar Disorder, posted by ed_uk on January 3, 2005, at 20:28:53
> To everyone with bipolar disorder...........
>
> In your own personal experience.........
>
> Which ADs *have not* induced mania, hypomania, mixed affective states or rapid cycling?
>
> Which ADs *have* induced mania, hypomania, mixed episodes or rapid cycling?
>
>
> PS. What do you think of the common pdoc attitude that TCAs are particularly likely to present problems in this respect? ....and that SSRIs and Wellbutrin are preferable. This doesn't seem particularly consistent with babblers' experiences. YMMV.
I would have to say that probably Trazodone was the only AD that didn't seem to "set off" anything, but it didn't work as an antidepressant either for me. I was taking it for sleep only (up to 100mg hs at one point) and it didn't even work for my sleep maintenance issues (I just went to sleep even faster, but that wasn't the problem anyhow) and left me hung over the next day.Remeron and Wellbutrin didn't seem to set off CYCLING, but they DID set off a consistently irritable/agitated and sometimes euphoric state.
Nortriptyline was fairly benign actually.
Never tried any MAOI's.
SSRI's seem to be the definite cycling champions, and I've been on all of those.
To assume that one particular class of med will induce mania and this particular class will not for *all* patients would be foolish. You really can't tell until you take them, IMO.
Posted by Maxime on January 4, 2005, at 21:28:04
In reply to Antidepressants and Bipolar Disorder, posted by ed_uk on January 3, 2005, at 20:28:53
Parnate is the only antidepressant that has not brought on mania for me and that includes all ssri, most TCA and everything in between (wellbutrin, effexor).
Max
Posted by cache-monkey on January 5, 2005, at 20:24:05
In reply to Antidepressants and Bipolar Disorder, posted by ed_uk on January 3, 2005, at 20:28:53
Hi Ed,
Let me caveat this by saying that I suspect a mild form of bipolar for myself, something like cyclothymia. The diagnosis is not clear, though, to either my therapist or pdoc.
That being said...
Celexa: (in combination with Wellbutrin) seems to have set off a hypomania, although mild. (I think that this was partially just truly feeling non-depressed. But I made some kind of "yeah this feels good, so just go ahead and do it" sorts of decisions that I've made during other "up" periods. Again, not clear if it's hypomania or the poor judgement ability of youth.) My general impression is that SSRIs are more likely than TCAs to induce mania. But I have absolutely no basis on which to back up that assertion.Wellbutrin, Serzone, Serzone+BuSpar, Buspar mono: nothing in the manic departnent. Wellbutrin was energizing and made me more driven, possibly obsessive. Serzone just flat out made me worse, especially with respect to my anxiety, which is the predominant symptom for me. BuSpar seems to have helped with certain aspects of my anxiety, but might also be making others worse.
Just started Lamictal (along with low-dose 7.5 mg/day BuSpar in the background) and upping from 25 to 50 mg seemed to make me hypomanic for a day, and then really tired and anxious. And then, finally, I had a full-blown panic attack. Granted there's some other pretty stressful stuff going on for me right now. But, the Lamictal was really the destabilizing factor. Since going back down to 25 mg, I'm just stuck with my "usual" problems.
HTH,
cache-monkey> To everyone with bipolar disorder...........
>
> In your own personal experience.........
>
> Which ADs *have not* induced mania, hypomania, mixed affective states or rapid cycling?
>
> Which ADs *have* induced mania, hypomania, mixed episodes or rapid cycling?
>
>
> PS. What do you think of the common pdoc attitude that TCAs are particularly likely to present problems in this respect? ....and that SSRIs and Wellbutrin are preferable. This doesn't seem particularly consistent with babblers' experiences. YMMV.
Posted by stresser on January 9, 2005, at 15:05:18
In reply to Re: Antidepressants and Bipolar Disorder, posted by Maxime on January 4, 2005, at 21:28:04
I was reading your posts and am intested in some information. Are you saying that you are bipolar and wellbutrin brought on mania? Can you define the mania for me? Did the mania stop when you stopped taking the SSRI's or Wellbutrin? -L
This is the end of the thread.
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