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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by ed_uk on January 10, 2005, at 19:19:35
Hi!
If you've been on both of the above, which did you prefer and why?
Thank you,
Ed.
Posted by mmcconathy on January 10, 2005, at 19:32:23
In reply to Adderall vs Dexedrine, posted by ed_uk on January 10, 2005, at 19:19:35
Dexedrine, more powerful and rapid with a kick.
Adderall is more slower acting, it feels the same at peak levels, but its less noticable when its coming on, but it is still as reforcing at the peak dose.
Dexedrine is just pure dextroamphetamine, by itself, adderall is 75% dextroamphetmaine and 25% levoamphetamine.
Adderall does in a way when its at its "fullest" make you feel more "charged", than dexedrine, becuaes it has levoamphetamine which is only works on psychical properties
Levoamphetmaine does not have any psycho-active properties, only it is acutally used here in the states in the Vicks vapor inhaler for nasal congestion. It effects more on cardio systems, this is why adderall maybe feels more energizing at times, it speeds up pulse rate more than Dex.
But addreall slowly wears off too, so its more "smooth".
I take Adderall 60mg right now, i was on Dexedrine 45 mg which is almost equivilant to the 60mg, since its more potent in dosage. But im just switching around to see, how which is diffrent.
But out of all of them Desoxyn is the all time winner since it is methamphetmaine, causes more aggression than regular ampjhetamine, mainly why it is frankly avoided.
Your Welcome
Posted by lunesta on January 10, 2005, at 19:43:31
In reply to Adderall vs Dexedrine, posted by ed_uk on January 10, 2005, at 19:19:35
listen to mmcconathy, he took the words from my mouth.
The L side of amphetamine is usually the one that causes the unpleasent side effects
I would go with Dexedrine by far.
lunesta
Posted by CareBear04 on January 10, 2005, at 22:52:45
In reply to Re: Adderall vs Dexedrine » ed_uk, posted by lunesta on January 10, 2005, at 19:43:31
thanks for this post-- very interesting. i've only been on adderall, and when i asked my pdoc about dexedrine, she said it would be more of the same thing. i definitely notice an increase in heart rate on adderall. i take about 50mg a day. of all the stimulant-type drugs i've been on (strattera, provigil, high-dose wellbutrin, ritalin, concerta), adderall is by far the best. does anyone know, though, whether adderall really raises blood pressure in addition to pulse, and if so, how much? one more question-- is dexedrine more or less or equally appetite-suppressing as adderall? this has been a problem for me. concerta, i've found, is less so than adderall, but it's also less overall effective. intersted in hearing more about dexedrine. thanks!
Posted by jonh kimble on January 11, 2005, at 2:45:34
In reply to Re: Adderall vs Dexedrine, posted by CareBear04 on January 10, 2005, at 22:52:45
mmcconathy, I thought that adderall was 50 - 50 d and l amphetamine? Are you sure about this 75 - 25? This would make more sense, but then based on what you say that l amph. has no mental effects, I wonder why they would bother putting it in an add treatment at all.
Anyway to answer the question, Im taking adderall now and I like it better because I feel it where I didnt really feel dexedrine. However, I take 30 mgs adderall and at times at least, was only on the 15mg of dex a day so this is not a completely fair compairison. However, 2 15 mg split doses still wasnt as good, tho that was long ago, and im much more in tune with drugs effects then I was back then.
I like amphetamines quite a bit better then ritalin because they dont cause as much ruminating, anxiety, perfectionism, etc... cause more appetite loss,(could be prob. for some obviously) and possibly due to or tied in with anxiety being lower are just more effective at helping me concentrate. The XR versions (all Ive tried) last looonngg tho, maybe even 14 - 16 hours so for me I take it the moment I wake up or really just cant, or at least shouldnt. Theres a reason Im typing this at 4:00 AM:) Viel gluck (good luck in german)Tom
Posted by sgoose on January 11, 2005, at 3:54:47
In reply to Re: Adderall vs Dexedrine, posted by jonh kimble on January 11, 2005, at 2:45:34
Dexedrine wins in my house. Adderall made me feel more jittery, like too much coffee. The explanation for that is already in this thread.
Posted by med_empowered on January 11, 2005, at 9:15:55
In reply to Adderall vs Dexedrine, posted by ed_uk on January 10, 2005, at 19:19:35
I like adderall the most. I think the levoamphetamine is in there b/c adderall was once a diet drug (Obetrol, I think...Andy Warhol loved the stuff), so it makes since to have amphetamines acting both in the brain and in the body...boosts its power as a diet drug. Anyway, I take 60mg adderall along with antidepressants...for me, the best part is that adderall seems to have a stronger antidepressive effect than dexedrine, especially when combined with antidepressants.
Posted by mmcconathy on January 11, 2005, at 13:13:40
In reply to Re: Adderall vs Dexedrine, posted by jonh kimble on January 11, 2005, at 2:45:34
You are thinking of the older medication Benzedrine, which i belive was removed from the market. It was racimatic pure amphetamine. Exactly 50 of Dextro and 50 of levo. It was not nearly as potent as Dexedrine.
Here is evidence that Adderall is a "cocktail" of diffrent amphetamine salts:
http://www.add-adhd-help-center.com/adderall_side_effects.htmhttp://www.healthsystem.virginia.edu/internet/pediatrics/hcp/ADHDAdderall.cfm
http://www.rxlist.com/cgi/generic/amphet.htm
My theroy on why they Made Adderall, when already the use of dexedrine was effective.
Adderall has a slightly longer half life, like an hour, and it seems to give a feeling of psychical stimulation, more than dexedrine, mainly to the added LevoAmphetamine. This can be more effective in treating "very hyper" active children.Good Day
Posted by alohashirt on January 11, 2005, at 23:39:56
In reply to Re: Adderall vs Dexedrine, posted by med_empowered on January 11, 2005, at 9:15:55
Dexedrine feels smoother than Adderall to me.
Less jittery. If anything, both of them increase my appetite.
P.S. - you should absolutely monitor your BP if you're using either. High blood pressure is a common side effect for some people.
Posted by ed_uk on January 12, 2005, at 4:13:33
In reply to Re: Adderall vs Dexedrine, posted by alohashirt on January 11, 2005, at 23:39:56
Hello,
>If anything, both of them increase my appetite.
Methylphenidate (Ritalin) does sometimes increase appetite!
J Clin Oncol. 2003 Dec 1;21(23):4439-43. Related Articles, Links
Patient-controlled methylphenidate for the management of fatigue in patients with advanced cancer: a preliminary report.Bruera E, Driver L, Barnes EA, Willey J, Shen L, Palmer JL, Escalante C.
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M.D. Anderson Cancer Center, Unit 8, 1515 Holcombe Blvd, Houston, TX 77030, USA. ebruera@mdanderson.org
PURPOSE: To assess the effects of patient-controlled methylphenidate for cancer-related fatigue. PATIENTS AND METHODS: In this prospective open study, 31 patients with advanced cancer and fatigue who scored >/= 4 on a scale of 0 to 10 received methylphenidate 5 mg by mouth every 2 hours as needed for 7 days (maximum, 20 mg/d). Multiple symptoms were assessed daily; the primary end point, fatigue, was measured using the 0 to 10 scale, and the Functional Assessment for Chronic Illness Therapy-Fatigue (FACIT-F) was performed at baseline, day 7, and day 28. RESULTS: The following mean (+/- standard deviation) scores for 30 assessable patients improved significantly between baseline and day 7: fatigue (0 to 10 scale), 7.2 +/- 1.6 v 3.0 +/- 1.9 (P <.001); overall well-being (0 to 10 scale), 4.5 +/- 2.2 v 2.8 +/- 2.1 (P <.001); fatigue (FACIT-F) subscore, 17.5 +/- 11.3 v 34.7 +/- 10.0 (P <.001); functional well-being, 14.4 +/- 5.9 v 18.3 +/- 6.6 (P <.001); and physical well-being, 13.5 +/- 6.4 v 21.4 +/- 5.0 (P <.001). Anxiety, appetite, pain, nausea, depression, and drowsiness all improved significantly (P <.05). All patients took afternoon or evening doses, and 28 patients (93%) took three or more doses daily. All patients chose to continue taking methylphenidate after 7 days of treatment. No serious side effects were reported. CONCLUSION: These preliminary results suggest that patient-controlled methylphenidate administration rapidly improved fatigue and other symptoms. Randomized controlled trials are justified.
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