Psycho-Babble Medication Thread 491041

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Big thing was mirapex, now its Selegeline

Posted by linkadge on April 28, 2005, at 16:21:10

A little while back, everyone was talking about their mirapex trials, now everones onto Selegeline. Whats the deal. Is mirapex a no go? Is anyone still on it ??

Thanks

Linkadge

Re: Big thing was mirapex, now its Selegeline

Posted by Chairman_MAO on April 28, 2005, at 16:53:43

In reply to Big thing was mirapex, now its Selegeline, posted by linkadge on April 28, 2005, at 16:21:10

Totally different mechanisms of action. The problem with DA agonists is that they tend to reduce DA release via autoreceptor stimulation (anyone ever try a DA agonist + amisulpride?). IMHO, mirapex in psychiatry is best looked at as a mood stabilizer with AD properties. It's also probably not half bad for the libido.

Re: Big thing was mirapex, now its Selegeline

Posted by linkadge on April 28, 2005, at 17:30:53

In reply to Re: Big thing was mirapex, now its Selegeline, posted by Chairman_MAO on April 28, 2005, at 16:53:43

I've never hear mirapex reffered to as a mood stabalizer, I was under the impression that psychosis is a fairly common side effect.

Thats what we need, a potent and selective dopamine autoreceptor antagonist.

Linkadge

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