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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by 4wd on October 7, 2005, at 21:06:42
I am too stressed and scared and anxious and depressed to understand or to research. Please explain in layman's terms why a D1 agnoist and D2antagonist help depression (and anxiety?)
Marsha
Posted by 4wd on October 7, 2005, at 21:51:46
In reply to Please tell me how Abilify helps with depression, posted by 4wd on October 7, 2005, at 21:06:42
Never mind. Found some post.
Marsha
Posted by Phillipa on October 7, 2005, at 21:56:57
In reply to Re: Please tell me how Abilify helps with depression, posted by 4wd on October 7, 2005, at 21:51:46
Marsha, where did you find it and what does it say? Fondly, Phillipa
Posted by 4wd on October 7, 2005, at 23:02:58
In reply to Re: Please tell me how Abilify helps with depression » 4wd, posted by Phillipa on October 7, 2005, at 21:56:57
> Marsha, where did you find it and what does it say? Fondly, Phillipa
Oh God, I don't remember now. It was a post of SLS's from a couple of years ago. Basically that it balances out dopamine in the brain - where there's not enough it increases it and where there's too much it decreases it. Some stuff about presynaptic autorecepters. I can't think.
Phillipa, I truly hope you get better on the Luvox. I prayed for you tonight.
Marsha
Posted by med_empowered on October 8, 2005, at 10:45:10
In reply to Re: Please tell me how Abilify helps with depression » Phillipa, posted by 4wd on October 7, 2005, at 23:02:58
hey! using antipsychotics (preferably at LOW doses) to help with some forms of depression has been done for a long, long time--Triavi, the perphenazine+Elavil combo, for instance, has been used since the '60s for this purpose. With the newer atypicals, research shows that combining them with antidepressants actually leads to an **increase** in the concentrations of key neurotransmitters that are often at lower levels during a depressive phase. Keep in mind, though, that any antipsychotic can induce depression if the dose is high enough. I took low dose abilify, and I think the best results are with abilify+antidepressant(s), with the abilify below 10mgs, unless you're having issues with psychosis, in which case it may be best to go up to 10-15mgs. Good luck!
Posted by 4wd on October 8, 2005, at 16:17:51
In reply to Re: Please tell me how Abilify helps with depressi, posted by med_empowered on October 8, 2005, at 10:45:10
> hey! using antipsychotics (preferably at LOW doses) to help with some forms of depression has been done for a long, long time--Triavi, the perphenazine+Elavil combo, for instance, has been used since the '60s for this purpose. With the newer atypicals, research shows that combining them with antidepressants actually leads to an **increase** in the concentrations of key neurotransmitters that are often at lower levels during a depressive phase. Keep in mind, though, that any antipsychotic can induce depression if the dose is high enough. I took low dose abilify, and I think the best results are with abilify+antidepressant(s), with the abilify below 10mgs, unless you're having issues with psychosis, in which case it may be best to go up to 10-15mgs. Good luck!
Thanks. That's what I'll be doing. I'm on Celexa but have residual anxiety, pretty severe, and a less than complete response to the Celexa. I'm prescribed 2.5 mg Abilify to start and I may start even lower since I'm a scaredy cat about new meds and it has such a long half life that if I get some awful akathisia it'll be with me for a long time.Marsha
Posted by Phillipa on October 8, 2005, at 17:12:30
In reply to Re: Please tell me how Abilify helps with depressi, posted by 4wd on October 8, 2005, at 16:17:51
Marsha, Thanks for praying for me. And please keep me posted on how you're doing on it and if it helps with anxiety. Fondly, Phillipa
Posted by 4wd on October 8, 2005, at 22:09:35
In reply to Re: Please tell me how Abilify helps with depressi » 4wd, posted by Phillipa on October 8, 2005, at 17:12:30
> Marsha, Thanks for praying for me. And please keep me posted on how you're doing on it and if it helps with anxiety. Fondly, Phillipa
You betcha. Wouldn't it be great if I took my first dose and my anxiety magically melted away and I suddenly felt like going out in the yard and planting a garden?Remember your thread about what your magic pill would do? That's what mine would do.
Marsha
This is the end of the thread.
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