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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by mike99 on March 7, 2006, at 15:08:00
Obviously everyone's mileage varies, but in general can anyone speak to how prevalent the risks/severity are for the following for a low dose of a beta-1 selective antagonist such as atenolol?ED
depression
fatigue
(physical)tolerance
insulin resistance--especially w/long term use
exercise intolerance
ED (yes I know I typed it twice =)
Posted by sdb on March 7, 2006, at 15:18:26
In reply to beta blocker side effects, posted by mike99 on March 7, 2006, at 15:08:00
It depends about the dosage you take and the response of your body.
ED: unlikely
depression: unlikely
fatigue: less likely
(physical) tolerance: diminished effect but no total tolerance
insulin restistance: less likely
exercise intolerance: depends what you're doing and dosage related~sdb
Posted by mike99 on March 7, 2006, at 19:52:13
In reply to Re: beta blocker side effects, posted by sdb on March 7, 2006, at 15:18:26
Thanks for the response, sdb.
Do you think if one were taking the lowest possible dose that it would still be likely to to say run a few miles, do moderately heavy weight-lifting?
Also, in terms of diminished effect but no total tolerance, does this mean that it is not likely there would be a need toward dose escalation to achieve the same effect with chronic use?
Just wondering if you'd happen to know.
Again, thanks for your input.
Mike
Posted by sdb on March 7, 2006, at 20:25:05
In reply to Re: beta blocker side effects » sdb, posted by mike99 on March 7, 2006, at 19:52:13
>Do you think if one were taking the lowest >possible dose that it would still be likely to >to say run a few miles, do moderately heavy >weight-lifting?
Yes absolutely possible. Sport is good in the overweight society. No sport is per se not malign but maybe too risky nowadays. But malign if you exercise 24h a day having similar effect of constant bloodpressure afterwards. If you exercise constantly (eg. 1h three times a week first) you will do things even better on a betablocker than before. But if you plan to do sport professionally on olympic niveau, you're probably no more able to reach the top. The betablocker would diminish your maximal power (diminished VO2max, less max. uptake of oxygen because of more limited heart rate in the pathway)
>Also, in terms of diminished effect but no >total tolerance, does this mean that it is not >likely there would be a need toward dose >escalation to achieve the same effect with >chronic use?
I would be cautious escalating the dosage. It's better to start low and look for a maintenance dosage. There are some betablockers without tolerance but its better to try it with atenolol first. Atenolol is a standard med in cardiology/heart surgery.
~sdb
Posted by mike99 on March 8, 2006, at 6:26:28
In reply to Re: beta blocker side effects, posted by sdb on March 7, 2006, at 20:25:05
Posted by CareBear04 on March 8, 2006, at 7:51:51
In reply to beta blocker side effects, posted by mike99 on March 7, 2006, at 15:08:00
Hi Mike,
The side effects really do vary not only from person to person but from time to time. THe first time I tried propranolol at the lowest dose, I got depressed within days and felt nauseated. Then later, I was able to take it at a high dose without any problems. I think I would second the opinion that it might help your performance by making you less shaky and more calm. Good luck!
CB
Posted by Phillipa on March 8, 2006, at 18:00:14
In reply to Re: beta blocker side effects » mike99, posted by CareBear04 on March 8, 2006, at 7:51:51
Took it too and it definitely made me tired til I adjusted to it and a slower pulse on excercise. Fondly, Phillipa
Posted by mike99 on March 9, 2006, at 5:48:49
In reply to Re: beta blocker side effects, posted by Phillipa on March 8, 2006, at 18:00:14
Posted by KarenRB53 on March 11, 2006, at 19:58:34
In reply to Re: beta blocker side effects » mike99, posted by CareBear04 on March 8, 2006, at 7:51:51
> Hi Mike,
> The side effects really do vary not only from person to person but from time to time. THe first time I tried propranolol at the lowest dose, I got depressed within days and felt nauseated. Then later, I was able to take it at a high dose without any problems. I think I would second the opinion that it might help your performance by making you less shaky and more calm. Good luck!I've been on propranolol for about a month now. My doctor said to start at .050mg 2x daily which I tried but really got depressed. Decreased to .050 1x daily still depressed and am now trying .025mg. nightly but still depressed. Is this common at such a low dosage?
Thanks, Karen
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