Psycho-Babble Medication Thread 624863

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Re: Any more studies done on SSRI/corscrew recepto

Posted by med_empowered on March 26, 2006, at 19:24:47

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 19:21:40

the last one i heard about was the rats study--you know, the one where young mice treated with prozac grew up to be depressed and anxious. Other than that..just some studies showing EPS and stuff.

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by linkadge on March 26, 2006, at 19:33:56

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by med_empowered on March 26, 2006, at 19:24:47

What bothered me the most was that, although the study used high doses of the drugs, the mice developed some of these alterations in as little as 4 days. So could taking lower doses for years produce the same results? I just can't take the pills untill the studies are there to show the contrary.


Linkadge


 

Re: Any more studies done on SSRI/corscrew recepto

Posted by linkadge on March 26, 2006, at 19:36:03

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by linkadge on March 26, 2006, at 19:33:56

WHen I'm was the SSRI's, it was easier to brush things like this off, well I guess because thats what the drugs do, they inhibit obsession. Even if it is (what I would now consider) healthy obsesson.

Linkadge

 

Re: Any more studies done on SSRI/corscrew receptors?

Posted by Glydin on March 26, 2006, at 19:51:15

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 19:21:40

I can understand your need for answers. It was just a question...... because in following your posts, I have noted a particular inquiring into the negative long term effects in the use of SSRI's versus any other class of AD's. I was curious about this. We do have differing viewpoints as to what "studies" really tell, but, I respect your views and realize you need to do what is comfortable for you.

 

Re: Any more studies done on SSRI/corscrew receptors? » Glydin

Posted by linkadge on March 26, 2006, at 20:23:18

In reply to Re: Any more studies done on SSRI/corscrew receptors?, posted by Glydin on March 26, 2006, at 19:51:15

Well this is it, although, I wouldn't call it what I feel is "comfortable".

The SSRI's have not been around long enough. Simply put, we lack long term safety data.

It is not guarenteed that what a doctor tells you about a medicaton is correct. Doctors have been incorrect in the past. It wasn't so long ago that fenfluramine was considered a safe weight loss drug.


Linkadge

 

Re: Any more studies done on SSRI/corscrew receptors?

Posted by Phillipa on March 26, 2006, at 20:30:08

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 20:23:18

No wonder my anxiety is so bad I'm confused confused confused!!!!!!!!Love Phillipa

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by djmmm on March 26, 2006, at 20:45:02

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 20:23:18

> Well this is it, although, I wouldn't call it what I feel is "comfortable".
>
> The SSRI's have not been around long enough. Simply put, we lack long term safety data.
>
> It is not guarenteed that what a doctor tells you about a medicaton is correct. Doctors have been incorrect in the past. It wasn't so long ago that fenfluramine was considered a safe weight loss drug.
>
>
> Linkadge
>
>


Here are a couple more negative studies:

http://www.antidepressantsfacts.com/toxicity-brain-damage.htm


 

Re: Any more studies done on SSRI/corscrew receptors? » linkadge

Posted by Glydin on March 26, 2006, at 22:32:43

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 20:23:18

Even though we differ on how we "see" things, I really do try to be respectful of how you "see" things. I don't feel there is any given back and I would really like get that but I'm thinking I'm not going to. While it's difficult to assess tone in the written word, I feel the tone is hostile.

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by SLS on March 27, 2006, at 6:54:56

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by djmmm on March 26, 2006, at 20:45:02

> > Well this is it, although, I wouldn't call it what I feel is "comfortable".
> >
> > The SSRI's have not been around long enough. Simply put, we lack long term safety data.
> >
> > It is not guarenteed that what a doctor tells you about a medicaton is correct. Doctors have been incorrect in the past. It wasn't so long ago that fenfluramine was considered a safe weight loss drug.
> >
> >
> > Linkadge
> >
> >
>
>
> Here are a couple more negative studies:
>
> http://www.antidepressantsfacts.com/toxicity-brain-damage.htm

The problem I see with this site is that it has an agenda. It does not produce a balanced or objective presentation. It is, obviously, a website devoted to the invalidation of antidepressants as a treatment for depression. However, many of the studies it cites seem to be legitimate and conducted with objectivity. The presentation can be very pursuasive, albeit biased. I think the site is a good resource if you are in urgent need of information to nullify the utility of antidepressants.


- Scott


 

Re: Any more studies done on SSRI/corscrew receptors?

Posted by linkadge on March 27, 2006, at 8:20:21

In reply to Re: Any more studies done on SSRI/corscrew receptors? » linkadge, posted by Glydin on March 26, 2006, at 22:32:43

My tone was not meant to be hostile, it was mean to be assertive.

I respect everybody's view. I don't necessarily agree with people's tendancy to presume the safety of the meds, but that does not mean I don't have respect for them as a person.

Linkadge

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by linkadge on March 27, 2006, at 8:21:55

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by SLS on March 27, 2006, at 6:54:56

I don't necessarily belive in the intentions of antidperessantfacts.com either. They do link to medline studies which we can process independantly.

Linkadge

 

ADs

Posted by med_empowered on March 27, 2006, at 8:58:23

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by linkadge on March 27, 2006, at 8:21:55

I think docs in general (and, for some reasons, psychiatrists in particular) tend to ignore the "Precautionary Principle": until something is proven safe (or at least the risks are known), you should minimize exposure. And if you look at all the treatments in psychiatry that came and went (barbiturates, quaaludes, common use of amphetamines) the big problem wasn't the chemicals per se--it was more over-prescribing b/c of "trends" in RXing and more patient selection and poor clinical management. The SSRIs have been used for EVERYTHING, which is one reason we have so many problems--if their use had been more limited, it probably wouldn't have been as problematic.

 

Re: Any more studies done on SSRI/corscrew receptors? » linkadge

Posted by Glydin on March 27, 2006, at 9:01:46

In reply to Re: Any more studies done on SSRI/corscrew receptors?, posted by linkadge on March 27, 2006, at 8:20:21

I was out of line when I posted that and I regret it. I apologize Link.

 

Re: Any more studies done on SSRI/corscrew receptors? » Glydin

Posted by linkadge on March 27, 2006, at 9:32:08

In reply to Re: Any more studies done on SSRI/corscrew receptors? » linkadge, posted by Glydin on March 27, 2006, at 9:01:46

You have every right to question my intentions.

Linkadge

 

Re: ADs » med_empowered

Posted by linkadge on March 27, 2006, at 9:46:03

In reply to ADs, posted by med_empowered on March 27, 2006, at 8:58:23

This is the thing. I have taken a difference stance, and that is guilty untill proven innocent.

I don't think that systematic studies have been done on a lot of the problems that are now surfacing, and I am really just wondering why?

We do thousands of studies that seem to show MDMA is capable of dammage to the serotonergic system, yet when one study seems to show the same with SSRI's there is no follow up? That doesn't make sence esp. since SSRI's are swallowed much more commonly then E.

I guess I am just wondering why psychiatry has to wait for problems to happen instead of being proactive?


Linkadge

 

Re: ADs

Posted by Meri-Tuuli on March 27, 2006, at 11:52:29

In reply to Re: ADs » med_empowered, posted by linkadge on March 27, 2006, at 9:46:03

Maybe doctors who do the studies showing that long term SSRI use isn't too healthy, get death threats from the Big Pharma companies....LOL

Seriously, it wouldn't surprise me.

Maybe there just isn't the funding - I take it that Pharma companies aren't going to specifically fund studies that show that their drugs aren't safe are they?

 

Re: ADs » Meri-Tuuli

Posted by linkadge on March 27, 2006, at 15:18:51

In reply to Re: ADs, posted by Meri-Tuuli on March 27, 2006, at 11:52:29

Good point. This is serious buisness for the drug companies. I'm sure they work to couteract all possibilities that might lead to sales decline.

Linkadge

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by vainamoinen on March 27, 2006, at 16:44:40

In reply to Any more studies done on SSRI/corscrew receptors?, posted by linkadge on March 26, 2006, at 17:00:05

My experience has been, after being on an SSRI for about 6 years now, that if I decrease the dosage in anything but an excruciatingly slow manner I go into a tailspin of depression.

So in a way it's not unlike methadone or heroin or any other addictive drug.

Now the flip side is that I am convinced that if it were not for antidepressants I would be dead by my own hand a long time ago.

So I'm strung out on prozac. Seems like a small price to pay for the quality of life I enjoy now.

And if I'm fattening the wallets of big pharm so be it. I'm also contributing towards their R&D budgets which may find a cure for cancer, heart disease, or diabetes.

The more cynical view would be that a cure for any of those maladies is not in the best interest of big pharm. But even a treatment of lifelong medication is better than the alternative is it not?

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by linkadge on March 27, 2006, at 19:03:20

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by vainamoinen on March 27, 2006, at 16:44:40

When I came off SSRI's my depression plunged to a level that it had never been before medicating. It stayed that way for a long time untill I felt somewhat like I did before taking the medications.

If I was to decide to medicate again, I would have to be prepared to face those consequences.

Linkadge


 

Re: Any more studies done on SSRI/corscrew recepto

Posted by summerflowers on March 28, 2006, at 6:43:15

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by linkadge on March 27, 2006, at 19:03:20

I used to think SSRIs on their own were as harmless as lollies.But something definatly permanantly changed in me since I went on and off them twice.I dont think their harmless anymore.

 

Re: Any more studies done on SSRI/corscrew recepto » summerflowers

Posted by linkadge on March 28, 2006, at 7:59:27

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by summerflowers on March 28, 2006, at 6:43:15

I find a lot of people are humbled by the first time they withdrawl from an AD for whatever reason.

I think that it is interesting how a lot of people's opinions change during/after withdrawl.

The drug goes from the best thing since sliced bread, to well, a little less than that.


Linkadge

 

Re: Any more studies done on SSRI/corscrew recepto

Posted by vainamoinen on March 28, 2006, at 14:32:38

In reply to Re: Any more studies done on SSRI/corscrew recepto » summerflowers, posted by linkadge on March 28, 2006, at 7:59:27


>
> I think that it is interesting how a lot of people's opinions change during/after withdrawl.
>


Ha, tell me about it. Even though the physical symptoms of Prozac withdrawal are nothing compared to the zaps you get from withdrawing from Effexor or Paxil, the depression is daunting. I dare say that the depression following AD withdrawal is worse than the depression the AD's were meant to treat. That's kinda effed up.

 

Re: Any more studies done on SSRI/corscrew recepto » vainamoinen

Posted by linkadge on March 28, 2006, at 15:47:36

In reply to Re: Any more studies done on SSRI/corscrew recepto, posted by vainamoinen on March 28, 2006, at 14:32:38

Its really effed up. It has been a year since being off SSRI's and many things for me aren't the same. I have problems walking that I can't seem to explain to doctors. Problems with ballance. My vision too was very dim for a long time after SSRI withdrawl. Another problem was that in myself the withdrawl depression included strong suicidiality where none had existed previously. I never suffered panic attacks either (anxiety but no panic attacks), during SSRI withdrawl I had some really bad panic attacks.

So while the drugs may help, people need to know about these things. If I had knew then what I know now, I would have not taken them.


Linkadge

 

Re: Any more studies done on SSRI/corscrew recepto » linkadge

Posted by Phillipa on March 28, 2006, at 19:36:34

In reply to Re: Any more studies done on SSRI/corscrew recepto » vainamoinen, posted by linkadge on March 28, 2006, at 15:47:36

That's it!!!!!!No more SSRI's for me. I've already cut down on the luvox and my anxiety is getting worse even with the valium. So link did the panic anc anxiety finally go away. Love Phillipa

 

Re: Any more studies done on SSRI/corscrew recepto » Phillipa

Posted by linkadge on March 28, 2006, at 21:53:20

In reply to Re: Any more studies done on SSRI/corscrew recepto » linkadge, posted by Phillipa on March 28, 2006, at 19:36:34

Eventually the panic attacks subsided. But for information, If I had to do the withdrawl again, it would have been done more slowly.

There seems to be a tendancy to withdrawl faster and faster as you reach nothing. Don't fall into that tendancy.


Linkadge


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