Psycho-Babble Medication Thread 841251

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wellbutrin sr initial efficacy / first few weeks?

Posted by frillyknickers on July 21, 2008, at 13:00:39

the first few weeks on wellbutin were some of the best weeks of my life in a long, long time honestly. it went away not long after that. we tried increasing the dose [150mg to start, upped to 300, then 450] but it didn't help much.

I went off it cold turkey at one point. when I went back on, I never experienced the same thing as those first few weeks.

this confused me quite a bit. it seems like it's not simple tolerance [increased dose does nothing, stopping it and starting it does nothing] so what IS this about?

I know I'm not alone because I've seen other people with similar stories about wellbutrin

 

Re: wellbutrin sr initial efficacy / first few weeks? » frillyknickers

Posted by Phillipa on July 21, 2008, at 13:47:01

In reply to wellbutrin sr initial efficacy / first few weeks?, posted by frillyknickers on July 21, 2008, at 13:00:39

Seems like it happens with all the ad's. Sorry. What does your doc suggest? Phillipa

 

Re: wellbutrin sr initial efficacy / first few wee » frillyknickers

Posted by raisinb on July 21, 2008, at 14:39:35

In reply to wellbutrin sr initial efficacy / first few weeks?, posted by frillyknickers on July 21, 2008, at 13:00:39

I wish I knew. The same thing happened to me.

My best guess is that the wonderful feeling is actually mild to moderate hypomania, which is a common startup side effect of WB.

Or, if you are like me and this happens with other ADs, too, it might be something to do with how quickly you metabolize drugs. Which has to do with weight, metabolic rate, current levels of neurotransmitters, etc.

Others on this site, I'll bet, though, could give a much more technical explanation.


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