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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by ttee on May 27, 2006, at 7:53:27
I read that there is currently a new study to patent a low dose (3,6,9mg) of Doxepin as an insominia med. Anyone have experience using low dose Doxepin for sleep in combo with AD's?
Supposedly, the ultra low doses are void of the typical TCA side effects.
Posted by Larry Hoover on May 27, 2006, at 9:32:01
In reply to Doxepin for Sleep?, posted by ttee on May 27, 2006, at 7:53:27
> I read that there is currently a new study to patent a low dose (3,6,9mg) of Doxepin as an insominia med. Anyone have experience using low dose Doxepin for sleep in combo with AD's?
>
> Supposedly, the ultra low doses are void of the typical TCA side effects.I'm experimenting with it, yes. But not as low as that, dose wise. Maybe I should try that. I've been at around 20 mg.
I think it is an excellent augment, when compared to e.g. trazadone. It's just getting the dose right that's tough, as it has very powerful histamine receptor affinity. That's a very sensitive receptor to play around with.
To say it is void of side effects might be a little much. But then again, I get strong side effects all the time.
Lar
Posted by naughtypuppy on May 27, 2006, at 11:23:54
In reply to Doxepin for Sleep?, posted by ttee on May 27, 2006, at 7:53:27
Tricyclics are often very good because of the antihistamic effects. I find 10mg of doxepin works just fine with no side effects, but 20mg makes me constipated.
Posted by Phillipa on May 27, 2006, at 21:26:07
In reply to Re: Doxepin for Sleep? » ttee, posted by Larry Hoover on May 27, 2006, at 9:32:01
Lar you get side effects too? For some reason I thought you must be supernatural. Love Jan
Posted by Colleen D. on May 28, 2006, at 22:48:42
In reply to Doxepin for Sleep?, posted by ttee on May 27, 2006, at 7:53:27
and have for more than two years. 25mg works well for me. I've never tried a smaller dose because 25mg is what my doc prescribed. I think that whoever is marketing the lower dose caps is very smart, since there are so many problems with other types of sleep-aid drugs. Doxepin is a natural choice when its neurotransmission effects are considered, and it really has no tolerance issues!
Colleen
BTW, I take Lexapro and clonazepam too.
Posted by pulse on May 29, 2006, at 18:01:31
In reply to Doxepin for Sleep?, posted by ttee on May 27, 2006, at 7:53:27
Interested, so I just googled. Said it will be called Silenor and, rather, in 1, 3, and 6 mg.
I hope this one gets passed, as I think I could tolerate the 1 mg., and possibly even the 3 mg. (Hopefully, then, no more quite substantial degrees of both reflux and constipation - as I've gotten with doxepin/ sinequan as I've grown older... at only 10 mg.)
thanks for the heads up.
pulse
Posted by yxibow on May 30, 2006, at 13:57:03
In reply to Doxepin for Sleep?, posted by ttee on May 27, 2006, at 7:53:27
I'm not sure about low dose, but at any dose, an adjustment period is necessary to overcome the antihistamine effect. It will knock you out cold, most likely the first time around. Best to start out on a weekend.
Posted by ANSKEL on January 31, 2009, at 20:04:56
In reply to Re: Doxepin for Sleep?, posted by yxibow on May 30, 2006, at 13:57:03
I have used up to 75 mg of doxepin along with clonopin. Definitely makes you sleep, but the quality of sleep is not the same.
I currenly use Ambien during the week and am experimenting with lower doses (although not that low) on the weekends. Using doxepin irregularly definitely increases the groggy effect the next day. Maybe the low dose regimen is the solution. ANSKEL
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