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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by ander35 on April 22, 2011, at 19:44:12
I saw online that these two drugs :may" cause TD. I noticed I open my mouth sometime to relieve jaw tension but I don;t do it in public. Do these drugs cause TD and if so is it permanent?
Posted by SLS on April 23, 2011, at 6:05:33
In reply to tardive dyskenisa and priztiq/Efeexor?, posted by ander35 on April 22, 2011, at 19:44:12
> I saw online that these two drugs :may" cause TD. I noticed I open my mouth sometime to relieve jaw tension but I don;t do it in public. Do these drugs cause TD and if so is it permanent?
I think Linkadge can shed light on this subject.
As for me, I don't believe that SRI medications can cause tardive dyskinisia. I do believe that they can produce akathisia, but you probably would have used other words to describe what you are experiencing. Akathisia is a severe form of restlessness with the inability to sit or stand still. What you are describing is consistent with bruxism (teeth-clenching) a side effect that often occurs with SRI drugs. It is usually benign and can disappear with time or upon therapeutic response to drug treatment. However, if you have TMJ, this side effect can make things worse, especially if it persists during sleep.
I came across a paper that describes the use of tandospirone to mitigate SSRI-induced bruxism. This drug is similar to buspirone and gepirone in that it acts as a partial agonist at serotonin 5-HT1a receptors. Gepirone was approved by the FDA, but probably isn't available yet. Gepirone adds serotonin reuptake inhibition, so one might need watch for serotonin syndrome when added SRIs. Buspirone (Buspar) is available, but adds some dopamine receptor blockade as a property. This might make buspirone undesirable as a remedy. That said, buspione sometimes acts to potentiate the the therapeutic response to antidepressants. I don't know for which antidepressants buspirone works best, but I am guessing SRIs. Since buspirone does not inhibit the reuptake of serotonin, it might make a safer choice. Tandospirone, an experimental drug, would be ideal.
- Scott
Posted by Christ_empowered on April 23, 2011, at 21:32:09
In reply to tardive dyskenisa and priztiq/Efeexor?, posted by ander35 on April 22, 2011, at 19:44:12
Effexor and Prozac have been linked to TD after long term (and I think high dose) treatment. Unlike antipsychotics, it probably won't pop up in the first year.
I think Effexor can also cause teeth grinding, which may be why your jaw sometimes feels tense (I don't know, just throwing that out there). TD is a lot different; you'd be looking for tongue darting, involuntary grimacing, involuntary movements of the fingers, that sort of thing.
If I remember correctly, some of the standard TCA drugs have been linked to TD, also.
Posted by SLS on April 24, 2011, at 4:46:12
In reply to Re: tardive dyskenisa and priztiq/Efeexor?, posted by Christ_empowered on April 23, 2011, at 21:32:09
> Effexor and Prozac have been linked to TD after long term (and I think high dose) treatment. Unlike antipsychotics, it probably won't pop up in the first year.
>
> I think Effexor can also cause teeth grinding, which may be why your jaw sometimes feels tense (I don't know, just throwing that out there). TD is a lot different; you'd be looking for tongue darting, involuntary grimacing, involuntary movements of the fingers, that sort of thing.
>
> If I remember correctly, some of the standard TCA drugs have been linked to TD, also.
I am having trouble finding literature associating antidepressants with tardive dyskinesia. Could you point me in the right direction?Thanks.
- Scott
Posted by Lou Pilder on May 1, 2011, at 19:15:09
In reply to Re: tardive dyskenisa and priztiq/Efeexor? » Christ_empowered, posted by SLS on April 24, 2011, at 4:46:12
Friends,
If you are considering being a discussant in this thread, I am requesting that you view the following video.
Lou
to see this video:
A. Pull up Google
B. Type in;
[youtube, Dystonia progressive from antidepressants & brain damage]
This usuall is first and there is a pic of a woman posted on Dec 4 2008... time is 6 min
This is the end of the thread.
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