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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by farshad on January 30, 2018, at 9:59:58
Would this be a safe combo?
300mg wellbutrin
10mg abilify
30mg Memantine
daily
Posted by Christ_empowered on January 30, 2018, at 10:15:42
In reply to Wellbutrin + abilify + memantine, posted by farshad on January 30, 2018, at 9:59:58
hi. what would you want these drugs for? wellbutrin is a stimulating drug used for smoking cessation and some forms of depression. abilify is a newer tranquilizer that has improved tolerability over, say, Haldol or Thorazine.
if you need a drug for depression or to stop smoking, then wellbutrin might be OK. it has its own set of adverse effects, but i did find it easier to tolerate and easier to stop than ssri or ssnri drugs.
if you need a tranquilizer for psychosis or severe mood problems, abilify might be an acceptable option. it causes less weight gain than many 'atypicals,' and it may cause less tardive dyskinesia than -some- other options, but even that advantage might not be as great as once thought/assumed.
memantine is a neurology drug, for alzheimer's. any use in psychiatry is off label and somewhat experimental.
be very careful with drugs, including prescription psych drugs. altering brain chemistry can cause problems, and that's not even factoring in all the other things that can go wrong (akathisia, drug induced depression, mania, psychosis, dependence, tardive dyskinesia, weight gain, diabetes, tardive dysphoria, tardive psychosis).
if you have severe problems that respond to available psych drugs, try to work with a prescriber to get on a drug (or drugs) that help improve your quality of life w/o causing too many problems.
Posted by farshad on January 30, 2018, at 10:27:37
In reply to Re: Wellbutrin + abilify + memantine, posted by Christ_empowered on January 30, 2018, at 10:15:42
> hi. what would you want these drugs for? wellbutrin is a stimulating drug used for smoking cessation and some forms of depression. abilify is a newer tranquilizer that has improved tolerability over, say, Haldol or Thorazine.
>
> if you need a drug for depression or to stop smoking, then wellbutrin might be OK. it has its own set of adverse effects, but i did find it easier to tolerate and easier to stop than ssri or ssnri drugs.
>
> if you need a tranquilizer for psychosis or severe mood problems, abilify might be an acceptable option. it causes less weight gain than many 'atypicals,' and it may cause less tardive dyskinesia than -some- other options, but even that advantage might not be as great as once thought/assumed.
>
> memantine is a neurology drug, for alzheimer's. any use in psychiatry is off label and somewhat experimental.
>
> be very careful with drugs, including prescription psych drugs. altering brain chemistry can cause problems, and that's not even factoring in all the other things that can go wrong (akathisia, drug induced depression, mania, psychosis, dependence, tardive dyskinesia, weight gain, diabetes, tardive dysphoria, tardive psychosis).
>
> if you have severe problems that respond to available psych drugs, try to work with a prescriber to get on a drug (or drugs) that help improve your quality of life w/o causing too many problems.
>
>would they be safe to take together? Memantine I tried got it over the internet and it worked great for my social anxiety. Wellbutrin because it increases noreheprine (however u spell that) and since its an weak dopamine agonist I wanna add low dose abilify to increase dopamine ..
Posted by SLS on January 30, 2018, at 15:24:28
In reply to Re: Wellbutrin + abilify + memantine, posted by farshad on January 30, 2018, at 10:27:37
> would they be safe to take together? Memantine I tried got it over the internet and it worked great for my social anxiety. Wellbutrin because it increases noreheprine (however u spell that) and since its an weak dopamine agonist I wanna add low dose abilify to increase dopamine ..
You might consider adding Lamictal to the Wellbutrin and Abilify. This combination works well for some people with TRD. I'm not sure why. However, it is my guess that Lamictal increases dopaminergic activity in the nucleus accumbens by inhibiting glutamate release in the hippocampus.
- Scott
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