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Re: Does Wellbutrin inhibit cyp450-2d6

Posted by JohnX2 on November 19, 2001, at 22:30:21

In reply to Re: Does Wellbutrin inhibit cyp450-2d6 » SLS, posted by SLS on November 19, 2001, at 18:43:45


I have a link to that table you pointed to,
I usually use it to look for drug interactions.
It still seems as though I see conflicting reports
on Wellbutrin and cyp 450-2d6. The latest pdr
showed it inhibited the enzme but other studies
showed little interactions. Maybe this data
is more recent.

regards,
john


> > >
> > > Does wellbutrin inhibit the liver enzyme cyp-450 2d6?
> > > I've seen references that go both ways.
> > >
> > > thanks for any feedback,
> > > john
> >
> >
> > Hi John.
> >
> > Have you seen this site yet?
> >
> > http://medicine.iupui.edu/flockhart/
> >
> >
> > - Scott
>
>
> I see that this webpage does not include information for bupropion.
>
> I found this:
>
> "Bupropion inhibits metabolism by cytochrome P450 2D6. Caution is advised when medicinal products metabolised by this enzyme are administered concomitantly."
>
> http://www.ash.org.uk/html/cessation/zybanspc0501.pdf
>
> Zyban TM (Bupropion hydrochloride)
> SUMMARY OF PRODUCT CHARACTERISTICS
> May 2001 (provided by GlaxoSmithKline)


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poster:JohnX2 thread:84667
URL: http://www.dr-bob.org/babble/20011113/msgs/84727.html