Posted by Ritch on February 12, 2002, at 10:19:53
In reply to Re: hypomanic again ugh; Zyprexa/Neurontin Questions? » Ritch, posted by JohnX2 on February 12, 2002, at 0:51:23
John, Just personal experience. They *work* great right after you take them, but there is a "rebound" effect they seem to have after they begin to "unoccupy" the D2 receptors, which feels worse than you did before you take them. Even the conventionals would do that to me. I remember small doses of Stelazine would make me feel better for most of the day, but in the evening I would start getting very anxious-like a mixed state, yuck! Of course, this could all just be akathisia. I remember when I took Seroquel-I really noticed it. I would feel pretty mellow during the day and then at nite just before my next dose I would get this "rocketing" like hypomania. So, my pdoc just told me to try to get by without antipsychotics. I know for some that might not be easy to do.
Mitch
>
> Hi Mitch,
>
> What leads you to believe the APs are destabilizing?
>
> I really would love to drop my Zyprexa and Neurontin
> and narrow my medicines down to Topamax + Lamictal.
> Less is more. I was taking the Zyprexa before I found
> the Topamax. The Neurontin is just short term to help with
> Klonopin withdrawl.
>
> -John
>
>
>
>
>
> > >
> > > Well after my latest crash I got nervous and
> > > decided to go back to my formula before I crashed
> > > which meant dropping my Zyprexa dose to 10 mg from
> > > 15 mg and restarting Neurontin 300 mg TID.
> > > I was taking Neurontin to help with tingling from
> > > Klonopin withdrawl, but now I'm thinking that maybe
> > > it was having an anti-depressant boost too? Any thoughts
> > > here?
> > >
> > > Anyways its 2 days later and I'm back on
> > > Planet John (hypomanic). It could be the combo of
> > > the 2 med changes plus my latest Klonopin drop. Ugh, I can't wait
> > > for this Klonopin taper to end so I can see where
> > > my brain's thermostat is really at.
> > >
> > > My pdoc wanted me to up the Zyprexa to 20 mg when I told him I was
> > > depressed, but It made me nervous and I did the opposite (dropped
> > > back to 10 mg, the old formula). Am I making a mistake.
> > > I tend to scramble when I get depressed.
> > > Can too much Zyprexa poo-poo the mood?
> > >
> > > -John
> >
> >
> > Just an opinion, but I think for many bipolars the atypical AP's are destabilizing in the long run.
> >
> > Mitch
poster:Ritch
thread:93794
URL: http://www.dr-bob.org/babble/20020208/msgs/93861.html