Posted by fachad on March 19, 2002, at 1:59:10
In reply to d-amphetamine vs. l-amphetamine?, posted by MB on March 18, 2002, at 16:10:17
In my experience, Adderall caused the most side effects, including dry mouth, and pounding heart, nervousness, etc of any of the stimulants.
Dexedrine caused less than Adderall, but more than Ritalin.
Ritalin has the fewest perephial side effects.
I don't think anyone would disagree with this ranking of the "harshness" of the pstims.
In my experience, Ritalin has the most positive effect on mood, but some think Dexedrine is better for mood.
> OK, I need some advice. I am currently taking Adderall, Neurontin, Klonopin, and Serzone.
>
> --Started with Gabitril then Trileptal as mood stabablizers, couldn't tolorate (especially when Prozac was added to Trileptal) so switched to Neurontin which seemed fine.
>
> --Akathisia and anxiety on Prozac was so bad that added Klonopin.
>
> --Never could tolorate akathisia on Prozac (even at 5-10mg/day) so switched to Serzone by my request (figured 5HT-2a blockade = less akathisia), but have yet to be able to get up to the 400mg requested by doc (stuck at 200mg: postural hypotension and akathisia).
>
> --Titrated up to 45mg Adderall a day. This seems to be the only med of the bunch that has helped mood any.
>
> P-doc's recomended dosing schedule screwed me up and I was left to titrate doing times and sizes of those doses for the past month as I only speak with him monthly (this sparse assistence with med management will change shortly).
>
> Anyway, during the day, I sometimes come down with horrible sympathetic overstimulation (chills, cold sweats, goosebumbps, creepy/crawly scalp, etc). It seems that when the Adderall first "kicks in" it is nothing like this, yet later in the day, the stimulation becomes more "ephedrine-like", then gets better. Along with the "ephedrine-like" stage is usually a mood swing in the negative direction (irritability or start crying over nothing or feel completely dead inside).
>
> Could this be the action of the l-amphetamine? I've been told that the pharmacokinetics of the four different Adderall salts is unknown (true?). The Dr's Assistent recommended Concerta. Methylphenidate, I've been told is even *more* peripherally active than Amphetamine. Am I wrong? Am I barking up the wrong tree if I ask tomorrow (my consultation) to be switched to dextroamphetamine?
>
> --also, I'm wondering if Serzone could be increasing norepinephrine at such a low dose (i.e., exacerbating Adderall's sympathamimetic side effects).
>
> I feel like the Doctor should have the answer, but instead it seems up to me to figure this out. Everything he's tried so far has made me sicker.
>
> MB
poster:fachad
thread:98610
URL: http://www.dr-bob.org/babble/20020318/msgs/98748.html