Posted by SLS on June 25, 2010, at 19:24:39
In reply to TCA + Prozac combo for anhedonia?, posted by Economist on June 25, 2010, at 18:16:05
> Someone here recommended I add desipramine or some other TCA to my current Prozac regimen to help with the anhedonia. Anyone here been on this combination?
I have never tried this combination, but I have had limited success mixing Effexor and nortriptyline. The combination of Zoloft and nortriptyline is favored by some.
Any time you mix a TCA with either Prozac or Paxil, you must reduce the dosage of the TCA by at least half. These two SSRIs inhibit P450 2D6, the enzyme responsible for metabolizing the TCA, resulting in higher TCA blood levels.
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:952199
URL: http://www.dr-bob.org/babble/20100615/msgs/952204.html