Posted by Delna on November 17, 2012, at 11:43:23
In reply to Re: Zipra/Sulpr link? Scott? ALERT:mention of *S* word » Delna, posted by SLS on November 17, 2012, at 11:27:37
> Hi Delna.
>
> http://www.ncbi.nlm.nih.gov/pubmed/19337725
>
> :-)
>
>
> - Scott
>
>
> --------------------------------------------
>
>
> > > Abilify and Latuda are good choices according to the most current literature. If you feel that you need an energy boost, I would first establish Abilify, Lamictal, and Wellbutrin, and then consider adding minocycline afterwards.
> > >
> > > Sulpiride might poop out because dopamine D2 presynaptic receptors eventually upregulate and reduce the synthesis and release of dopamine, thus reversing the initial increase in DA release.
> > > Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade.
> >
> > If Abilify doesn't work, then Latuda makes a good second choice.
> > >
> > > -------------------------------------
> > >
> > > Effexor: 300 mg/day (Perhaps substitute Cymbalta for pain symptoms)
> > >
> > > Wellbutrin: 300-450 mg/day
> > >
> > > Lamictal: 200 mg/day
> > >
> > > Abilify: 2.0-10.0 mg/day
> > >
> > > Ritalin: 40 mg/day (Focalin might be better)
> > >
> > > Klonopin: 2.0 mg/day
> > >
> > > gabapentin: 900 mg/day
> > >
> > > -------------------------------------
> > >
> > >
> > > - Scott
> >
> >
> > Hi Scott,
> > thanks a lot for your reply!
> >
> > You said:
> > "Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade. "
> >
> > Did you mean lurasidone and ziprasidone have action at 5HT7? Or Lurasidone & Sulpiride?
> > I have not seen anything that talks about sulpiride and 5ht7 so if you've read that somewhere, that maybe the answer ! Because I am sure that Ziprasidone has action at 5HT7 and if sulpiride does as well, thats what links them!! Can you please tell me where you read about sulpiride and 5HT7?
> >
> > Then latuda would be worth a shot. It may really work!
> >
> > I tried Abilify. It was really uselss.
> >
> > My doctor wants me to take 400mg minocycline, then add mementine. That also acts on glutamate. Gabapentin is way too sedating. I could only tolerate it whilst on Geodon, when nothing could r oversedate me.
> >
> > Thanks again,
> > Your input is so helpful!
> > D
> >
>
>Hi Scott,
Thanks for the link. I can only see an abstract about amisulpiride but not sulpride.
poster:Delna
thread:1031452
URL: http://www.dr-bob.org/babble/20121113/msgs/1031465.html