Posted by pedr on November 13, 2017, at 10:55:01
In reply to Re: Residual anhedonia on Parnate » pedr, posted by SLS on November 12, 2017, at 21:06:05
> My personal experience with MAOIs is that Parnate can leave residual anhedonia, even at high dosages. Nardil is a stronger mood-brightener and is better at treating anhedonia. I found that adding nortriptyline helps with anhedonia when added to Parnate. Desipramine did not. However, it often happens that someone is inadequately treated with Parnate and never reaches a therapeutic level. You will find some variability in the literature, but I would say that the dosage range lies between 40-80 mg/day. You really can't evaluate the amount of residual anhedonia that Parnate leaves until it is titrated to a dosage that gives maximal effect, even if only a partial response. I'm sorry that your doctor is resistant to adding a stimulant. You could try to find literature that suggests that adding either nortriptyline or desipramine is not only safe to add to a MAOI, but might even mitigate the tryramine pressor response. Try Google or PubMed.
>
>
> - ScottScott, thanks so much for the post. I was on Nardil a few years ago and liked it except for the daytime somnolence that I just couldn't shake. I literally fell asleep at my desk on a number of occasions, even after being on Nardil for over a year.
I will try and get Nortriptyline added. This will mean finding a new PDoc as there's zero chance my current one will see past his "MAOI+TCA=instant death" mantra. I've shown him the psychotropical.info literature and he's not budging. Sigh.
Pete
I love the smell of Abilify in the morning. The smell, you know that chemical smell. Smells like victory. Some day this war's gonna end...
====
Atypical Depression, OCD, IBS-C, GERD since '96
poster:pedr
thread:1095844
URL: http://www.dr-bob.org/babble/20161215/msgs/1095854.html