Posted by bleauberry on July 25, 2008, at 20:35:09
In reply to D receptors: requip, bromcriptine, amantadine, posted by dcruik518 on July 24, 2008, at 14:13:07
I'm sure you already know, but just wanted to mention the other one Pramipexole. In clinical studies it was shown superior to the others for both depression and anxiety. Another one that has been used successfully by a couple people here is the mailorder Trivastel.
Amantadine has some unknown mechanisms in addition to the ones that are known, so it is anyone's guess. For example, it is anti-viral, and some dysthymias, depressions, chronic diseases of all sorts, have viral causes that result in nervous system inflammation and imbalance of neurotransmitters and such.
> Heloo, Hello,
>
> I've recently begun experimenting on myself with different dopaminergic drugs to see if they might help with my beautiful combination of dysthymia, social phobia, ADD, and spasmodic dysphonia. I started out with Requip, which seemed to work enthusiastically for about a week then turned its teeth on me and decided to exacerbate the voice thing. I then tried bromocriptine and to tell you the truth I really couldn't tell much difference--problems continued--but I kept using it as an effective sleep med, which I thought was maybe healthier than the Requipment. Now, finally, I've been taking the Amantadine which, so far, I think I like the best, though, it's a bit early to tell. Amantadine seems less sedating than the others--hence good for ADD; also my voice seems less spasmodic, and I feel more inclined to move up and around outside of the house. I'm not sure which dopamine receptors these drugs primarily affect, D3? Do you think the reason for the improvement with Amantadine might be the NMDA action, which I here can be pretty hot? I would really appreciate the help of you good people.
>
> ~Gandhi
>
>
poster:bleauberry
thread:841805
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/842055.html