Posted by JadeKelly on November 3, 2008, at 12:13:51
In reply to Re: PARNATE: rough start but WOW, posted by Medline on November 3, 2008, at 5:08:30
> I don't really understand Bulldog's answer too. Of course Lamictal could be a good augment to a MAOI, but it will do nothing for the blood pressure and can not replace Nifedipine as an antidote in case of hypertensive crisis.
>
> To reduce the risk of tyramine-rich food provoved hypertension, noradrenergic TCAs or NARIs like Reboxetine could be used. But such combos must be taken under supervision of psychiatrists very familiar with MAOIs and are usually reserved for very treatment resistent cases.Thanks for the resonse. I though he meant Lamictal would put ceiling on BP. My particular problem is unusual in that I went 11 days on Parnate, and felt great. Then out of the blue this hypertensive crisis. What has me baffled/worried is that I had spike in BP (185-190) after EVERY dose after that. Not food or drug induced. Wierd, huh? Elizabeth is only other poster I've seen with spontaneous hypertention. Have never corresponded with her, as just joined.
So its unlikely that Pdoc will have antidote that can be taken daily other than another type AD? I'm afraid to do that. Aren't they contraindicated? Do you feel these would be as effective as Nifedipine? As my spikes aren't related to food/drug reaction. That stuff works but the fatigue sorta offsets the benefits of the Parnate. So frustrating to finally find an AD that works to find that I may not be able to take it.
Btw-Any personal experience on these or similar drugs? I have TR/atyp MDD. Almost 3 years. Many triggers, but should be over it by now.Thanks!
Jade
poster:JadeKelly
thread:859759
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/860547.html