Posted by SLS on January 3, 2010, at 7:19:07
In reply to Re: 5-HT7 Receptors in Mood Disorders - New Hope?, posted by mtdewcmu on January 2, 2010, at 22:09:45
They don't mention that as a ligand, amisulpride is preferential for presynaptic receptors at low dosages. That this might produce an increase in the synthesis and release of dopamine without significant postsynaptic receptor blockade might contribute to its antidepressant properties.
- Scott
poster:SLS
thread:924322
URL: http://www.dr-bob.org/babble/neuro/20091104/msgs/932269.html