Psycho-Babble Medication Thread 890855

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TIaneptine + SSRI / SNRI ?

Posted by uncouth on April 15, 2009, at 9:35:53

Does anyone have any experience with combining tianeptine (stablon) with an SSRI or SNRI, both at full strength? I"m curious if they both essentially would negate each other, or if there is "other stuff" going on with tianeptine independent of it's serotonin accelleration, such that it wouldn't conflict with the SSRI.

Basically trying to throw everything at the wall here, seeing what's going to stick. Have a 20 day supply of tianeptine left and figured might as well go through it, hopefully it will have a positive effect on my mood although I am taking Effexor + Nortriptyline as well, and have milnacipran on order.

Love,
-A

 

Re: TIaneptine + SSRI / SNRI ?

Posted by desolationrower on April 15, 2009, at 12:44:24

In reply to TIaneptine + SSRI / SNRI ?, posted by uncouth on April 15, 2009, at 9:35:53

it might be worth trying with an nri; there was one animals study that prozac+stablon resulted in no anxiolysis whereas either alone was anxiolytic, so any sri i think should avoid with stablon

-d/r

 

Re: TIaneptine + SSRI / SNRI ?

Posted by Sigismund on April 15, 2009, at 16:07:19

In reply to TIaneptine + SSRI / SNRI ?, posted by uncouth on April 15, 2009, at 9:35:53

I have not much experience with AD combos, but here it is, as far as I remember.

SAMe and Parnate.............Agitating
SAMe and Tianeptine..........OK
Parnate and tianeptine.......Terrible

and then related

Hydergine and Trivastal......Good
Agomelatine and Hydergine....OK


I think it is unpredictable and difficult to get right. So I have not been in a hurry to combine agomelatine with anything much.


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